Old Dominion and USF Clash in 2025 Cure Bowl Showdown

The 2025 Cure Bowl pits the Old Dominion Monarchs against the South Florida Bulls on December 13, 2025, at Camping World Stadium in Orlando, Florida. Both teams enter this matchup with strong finishes to the season. Old Dominion concluded the regular season with five consecutive victories, while South Florida won its last two games and three of its final four.

Old Dominion boasts a record of 9-3, securing second place in the Sun Belt East Division with a conference record of 6-2. Throughout the season, they outscored their opponents by a total of 161 points. The Bulls, also at 9-3, finished tied for fourth in the American Conference and had a more substantial point differential, outscoring their rivals by 236 points.

Both teams will face significant changes in their lineups. Notably, quarterbacks Byrum Brown of South Florida and Colton Joseph of Old Dominion have opted out of the game. Additionally, South Florida’s head coach Alex Golesh and most of the offensive staff will not be present, as Golesh recently accepted a position at Auburn University.

Kickoff is scheduled for 17:00 ET, with South Florida opening as a 4-point favorite in the latest odds from SportsLine. The over/under for total points scored is set at 52.5, reflecting a drop of three points from the original line.

The SportsLine Projection Model, which simulates each FBS game 10,000 times, has provided insights into this matchup. The model has consistently shown profitability on its top-rated money-line picks since the start of the 2024 season. For those looking to place bets, new users can utilize the DraftKings promo code for $200 in bonus bets with a minimum wager of $5.

In terms of performance predictions, the model suggests that Old Dominion running back Trequan Jones will achieve over 80 rushing yards and score at least one touchdown. Meanwhile, the Bulls’ running backs, including Nykahi Davenport, Sam Franklin, and Alvon Isaac, are projected to collectively rush for over 100 yards. The model anticipates that the teams will combine for approximately 56 points, indicating a strong likelihood of surpassing the total points line.

As excitement builds for the Cure Bowl, fans and analysts alike will be keen to see how the absence of key players and coaching staff will influence the outcome. For those interested in the latest betting trends and expert predictions, resources such as SportsLine provide valuable insights into the game.

With the stakes high and both teams eager for victory, the 2025 Cure Bowl promises to be an electrifying contest. Fans can tune in for what is expected to be a thrilling conclusion to the college football season.